A chemostat array enables the spatio-temporal analysis of the yeast proteome.

Nicolas Denervaud (1,2), Johannes Becker (1,3), Ricard Delgado-Gonzalo (2), Pascal Damay (4), Arun S. Rajkumar (1,2), Michael Unser (2), David Shore (4), Felix Naef (1,3) & Sebastian J. Maerkl (1,2)

(1) Institute of Bioengineering, (2) School of Engineering, (3) School of Life Science, Ecole Polytechnique Federale de Lausanne, Switzerland (4) Department of Molecular Biology and NCCR program ”Frontiers in Genetics”, University of Geneva, CH-1211 Geneva, Switzerland

Online Database

This online database contains all movies acquired in our study. For each movie, we present a panel of plots, showing the results of our analysis pipeline. Raw images are also available for download.


Note: the movies require Google Chrome (other web-browsers are currently not supported (we are working on it).

Manuscript Files

Supplementary Information

Data Files

Bulk datafiles: Single Cell datafiles: Strain List:

Data Files (outdated)

Microfluidic Designs

Our microfluidic device design files can be found here

Gal screen


Biological Sciences - Systems Biology - Physical Sciences - Engineering:

Nicolas Dénervaud, Johannes Becker, Ricard Delgado-Gonzalo, Pascal Damay, Arun S. Rajkumar, Michael Unser, David Shore, Felix Naef, and Sebastian J. Maerkl

A chemostat array enables the spatio-temporal analysis of the yeast proteome

PNAS 2013 ; published ahead of print September 9, 2013, doi:10.1073/pnas.1308265110

manuscript html, manuscript pdf

Topic revision: r28 - 2015-06-26 - SebastianMaerkl
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